Professional production of centrifuge separator and pharmaceutical machinery manufacturer - Zonelink
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Professional production of centrifuge separator and pharmaceutical machinery manufacturer - Zonelink
How to use Pharmaceutical Medicine Automatic Rotary Tablet Machines Tablet Pill Press Making Machine?
The Rotary Tablet Machines is mainly used for the research on the film process of the pharmaceutical industry. The Rotary Tablet Machines the granular material into a circular, alien, and text, symbols with text, symbols, and graphic -like automatic continuous production equipment with a diameter of not more than 13mm. Some pharmaceutical Rotary Tablet Machines appear when the edge and dust should be used for dust removal (more than two times) when the slices are compressed, and the GMP specification must be met.
working principle
1. Chonghe Mo Mo: Chonghe Model is the basic component of the filmmaker. As shown in the figure, each punching mold consists of three components: upper, medium mode, and lower. The structure of the upper and lower punch is similar, and the diameter of its punching heads is equal. The upper and lower punching heads and the molded pores of the middle model can be freely slid up and down in the medium model hole, but there will be no gap between the gap that can leak the powder powder. Essence The size of the punch is a unified standard size and is interchangeable. The specifications of the formation are represented by the diameter of the punch or the medium-sized pores. Generally, it is 5.5-12mm, and every 0.5mm is a specification, with a total of 14 specifications.
The pressure of the punch and the punch is very stressful during the pressure. It is commonly used to make bearing steel (such as CRL5, etc.), and heat treatment to improve its hardness.
There are many types of punching, and the shape of the punching head determines the shape of the pills. The shape of the punching mold can be divided into circular, alien (including polygon and curve); the shape of the jumping section is plane, bevels, shallow concave, deep concave, and comprehensive form. Plane shape and beveled edge flush are used to suppress flat cylindrical sheet agents, shallow concave to suppress dual convex surface agents, and deep concave is mainly used to suppress the chip of coating doses. The comprehensive form is mainly used to suppress the suppression Alien sliced. In order to facilitate identification and taking medicines, the drug names, dosage and vertical lines can also be carved on the end surface of the mold. Pressing different doses of tablets should choose suitable punch with suitable size.
2. The working process of the filmmaker
The working process of the chip machine can be divided into the following steps:
① The punching part of the lower punch (its working location faces the top) from the lower end of the middle mold hole into the middle mold hole, and seal the middle mold hole bottom;
② Use the additional device to fill the medicine into the medium mold hole;
③ The punching part of the upper punch (its working position faces down) from the upper end of the middle mold hole to the middle mold hole, and down a certain itinerary to suppress the medicine powder into slices;
④ Raise the pores on the upper punch, push the pills out of the middle mold hole, and complete the process of pressing the film;
⑤ The lower rinse is dropped to the original position, and the next filling is prepared.
3. Principles of film compression mechanism
① Dose control. Various tablets have different dosage requirements. Large dosage adjustments are achieved by selecting different duster diameters, such as 6mm, 8mm, 11.5mm, 12mm, etc. After selecting the size of the mold, the tiny dose adjustment is to change the actual length of the medium -sized hole after the depth of the middle mold hole through the adjustment of the middle mold holes, and adjust the fill volume of the drug in the mold hole. Therefore, it should have an institution that rushes under the moldhole under the chip machine to meet the dosage regulation requirements. Because there are always differences in the comparison of different batch numbers, this adjustment function is very necessary.
In dosage control, the action principle of the feeder also has a considerable impact. For example, the particle drugs are self -weight, and the filling conditions are relatively loose when rolling into the middle mold hole. If multiple obsessive -compulsive situations are adopted, more drugs will be filled in the mold holes, and the filling conditions will be dense.
② Control of the thickness and compaction of the pill. The dose of the drug is determined according to the prescription and the pharmacopoeia, and it cannot be changed. In order to storage and transport, save and collapse the time limit, there is also a requirement for the pressure on a certain dose during crushing. It will also affect the actual thickness and appearance of the pills. The pressure adjustment when pressing is essential. This is achieved by regulating the downlink volume of rushing in the mold hole. Some crusher machines not only rush down and down in the process of pressing the film, but also have a down -to -up action action, and the process of completing the crushing process from the top and bottom relative movement. However, pressure regulation is mostly regulating and controlling by regulating institutions that rush down and down.
